
The 18β-glycyrrhetinic acid (NGA) nanocrystals prepared by adsorption of amphiphilic chitosan (ACS) with 10:1 optimal ratio of NGA to ACS was used to prepare ANGA composites, which was utilized to prevent and treat skin photoaging. The results of this article indicated that the NGAs could significantly enhance the photoaging of mouse skin, so the ANGA hydrogel could be used to counteract skin photoaging.