﻿{"id":1671,"date":"2020-12-10T10:04:46","date_gmt":"2020-12-10T02:04:46","guid":{"rendered":"https:\/\/www.bihec.com\/brimrose\/?p=1671"},"modified":"2020-12-10T10:26:08","modified_gmt":"2020-12-10T02:26:08","slug":"ackley-%e5%9c%a8%e5%88%b6%e8%8d%af%e7%89%87%e5%89%82%e6%bf%80%e5%85%89%e9%92%bb%e5%ad%94%e6%9c%ba%e4%b8%ad%e5%a2%9e%e5%8a%a0%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1%e4%bb%aa%ef%bc%8c%e5%8f%af","status":"publish","type":"post","link":"https:\/\/www.bihec.com\/brimrose\/ackley-%e5%9c%a8%e5%88%b6%e8%8d%af%e7%89%87%e5%89%82%e6%bf%80%e5%85%89%e9%92%bb%e5%ad%94%e6%9c%ba%e4%b8%ad%e5%a2%9e%e5%8a%a0%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1%e4%bb%aa%ef%bc%8c%e5%8f%af\/","title":{"rendered":"Ackley: \u5728\u5236\u836f\u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a\u4e2d\u589e\u52a0\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea\uff0c\u53ef\u4ee5\u7b80\u5316\u6e17\u900f\u836f\u7269\u7684\u8f93\u9001"},"content":{"rendered":"<h2><strong><a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/near-infrared-spectroscopy-for-controlled-release-tablets\/\" title=\"View all posts in Near-Infrared Spectroscopy for Controlled Release Tablets\" target=\"_blank\">Near-Infrared Spectroscopy for Controlled Release Tablets<\/a><\/strong><\/h2>\n<p><strong>Osmotic drug delivery has been simplified with the addition of <a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/nir\/\" title=\"View all posts in NIR\" target=\"_blank\">NIR<\/a> spectroscopy to <a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/ackley\/\" title=\"View all posts in Ackley\" target=\"_blank\">Ackley<\/a>\u2019s line of pharmaceutical tablet laser drilling machines.<\/strong><\/p>\n<p>The osmotic-controlled release oral delivery system, or OROS, is an advanced timed release mechanism usually in the form of a bi-layer tablet with a semi-permeable outer membrane which retains its integrity until it reaches the intestines. If this coating is damaged, the drug might release immediately after ingestion, which could be very harmful, or even fatal, to the consumer.<\/p>\n<p>NIR Inspection provides a quick and accurate way to verify that a tablet\u2019s enteric coating is acceptable and therefore safe for consumption. Near-infrared spectroscopy provides a unique advantage for pharmaceutical manufacturers due to its ease of use and fast, accurate analysis of solid dosage forms. This analytical technique uses the near-infrared region of the electromagnetic spectrum to provide a material signature that can be plotted to show peaks at specific wavelengths of light. This analysis provides information on a material\u2019s composition and can provide important information about the safety and quality of coatings on OROS tablets.<\/p>\n<p>Ackley\u2019s CO2 precision laser drilling machinery is now equipped with optional near-infrared spectroscopy in addition to vision inspection. Our Class 1 Laser tablet drilling machines drill sub-millimeter sized apertures into the enteric coating of single and bi-layer tablets to achieve the desired dissolution rate and drug release profile. This fully-integrated NIR inspection system provides and increased level of safety for consumers and additional peace of mind for pharmaceutical manufacturers by giving them twice the inspection power, ensuring that only the best products make it to market.<\/p>\n<p>Whatever your laser drilling needs, our engineering team is ready to design a solution that will give your controlled release product a perfectly aligned, precisely drilled aperture, each and every time.<\/p>\n<table>\n<tbody>\n<tr>\n<td><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-1673\" src=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-300x300.png\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-300x300.png?v=1607564922 300w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-1024x1024.png?v=1607564922 1024w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-150x150.png?v=1607564922 150w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-768x768.png?v=1607564922 768w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-500x500.png?v=1607564922 500w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08-800x800.png?v=1607564922 800w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-VIP-NIR-carousel-08.png?v=1607564922 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/td>\n<td><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-1674\" src=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-300x300.png\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-300x300.png?v=1607565224 300w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-150x150.png?v=1607565224 150w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-768x768.png?v=1607565224 768w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-500x500.png?v=1607565224 500w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08-800x800.png?v=1607565224 800w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Laser-Drilling-Ackley-Machine-Carousel-08.png?v=1607565224 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/td>\n<\/tr>\n<tr>\n<td>\n<p><figure id=\"attachment_1672\" aria-describedby=\"caption-attachment-1672\" style=\"width: 300px\" class=\"wp-caption alignnone\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1672 size-medium\" src=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-300x300.png\" alt=\"\u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-300x300.png?v=1607564919 300w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-150x150.png?v=1607564919 150w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-768x767.png?v=1607564919 768w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-500x500.png?v=1607564919 500w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03-800x800.png?v=1607564919 800w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/Osmotic-Laser-Drilling-Machine-VIP-NIR-03.png?v=1607564919 956w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-1672\" class=\"wp-caption-text\"><a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e7%89%87%e5%89%82%e6%bf%80%e5%85%89%e9%92%bb%e5%ad%94%e6%9c%ba\/\" title=\"View all posts in \u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a\" target=\"_blank\">\u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a<\/a><\/figcaption><\/figure><\/td>\n<td>\n<p><figure id=\"attachment_1378\" aria-describedby=\"caption-attachment-1378\" style=\"width: 300px\" class=\"wp-caption alignnone\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-1378 size-medium\" src=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/04\/4030\u7167\u7247-300x300.jpg\" alt=\"Brimrose\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea4030\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/04\/4030\u7167\u7247-300x300.jpg?v=1587043870 300w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/04\/4030\u7167\u7247-150x150.jpg?v=1587043870 150w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/04\/4030\u7167\u7247-500x500.jpg?v=1587043870 500w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/04\/4030\u7167\u7247.jpg?v=1587043870 561w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-1378\" class=\"wp-caption-text\"><a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/brimrose%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1%e4%bb%aa\/\" title=\"View all posts in Brimrose\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea\" target=\"_blank\">Brimrose\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea<\/a>4030<\/figcaption><\/figure><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Ackley\u4f7f\u7528\u4e0e<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/nasa\/\" title=\"View all posts in NASA\" target=\"_blank\">NASA<\/a>\u5728\u6708\u7403\u4e0a\u5bfb\u627e\u6c34\u76f8\u540c\u7684<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/brimrose\/\" title=\"View all posts in Brimrose\" target=\"_blank\">Brimrose<\/a><a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1%e4%bb%aa\/\" title=\"View all posts in \u8fd1\u7ea2\u5916\u5149\u8c31\u4eea\" target=\"_blank\">\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea<\/a><\/h2>\n<p>Ackley Machine Corporation is at the forefront of cutting-edge pharmaceutical equipment manufacturing. Our VIP Laser Drill + NIR features two fully-integrated\u00a0Brimrose <a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/aotf-nir\/\" title=\"View all posts in AOTF-NIR\" target=\"_blank\">AOTF-NIR<\/a>\u00a0Spectrometers, delivering fast-responding analysis of a tablet\u2019s enteric coating. This process ensures the integrity of each osmotic controlled release pharmaceutical product prior to laser drilling. This innovative use of near-infrared technology improves OROS production quality and consistency.\u00a0<em>(Photo courtesy of\u00a0Brimrose)<\/em><br \/>\n<img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-1678\" src=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01-297x300.jpg\" alt=\"\" width=\"297\" height=\"300\" srcset=\"https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01-297x300.jpg?v=1607566872 297w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01-768x776.jpg?v=1607566872 768w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01-495x500.jpg?v=1607566872 495w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01-792x800.jpg?v=1607566872 792w, https:\/\/www.bihec.com\/brimrose\/wp-content\/uploads\/sites\/192\/2020\/12\/NASA-Backdrop-LH-01.jpg?v=1607566872 985w\" sizes=\"(max-width: 297px) 100vw, 297px\" \/><\/p>\n<br><div class=\"tagcloud\"><a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/ackley\/\" class=\"tag-cloud-link tag-link-0 tag-link-position-1\" style=\"font-size: 8pt;\" aria-label=\"Ackley (1\u4e2a\u9879\u76ee)\">Ackley<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/brimrose\/\" class=\"tag-cloud-link tag-link-1 tag-link-position-2\" style=\"font-size: 22pt;\" aria-label=\"Brimrose (229\u4e2a\u9879\u76ee)\">Brimrose<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/near-infrared-spectroscopy-for-controlled-release-tablets\/\" class=\"tag-cloud-link tag-link-2 tag-link-position-3\" style=\"font-size: 8pt;\" aria-label=\"Near-Infrared Spectroscopy for Controlled Release Tablets (1\u4e2a\u9879\u76ee)\">Near-Infrared Spectroscopy for Controlled Release Tablets<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e6%8e%a7%e9%87%8a%e7%89%87%e5%89%82%e7%9a%84%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1\/\" class=\"tag-cloud-link tag-link-3 tag-link-position-4\" style=\"font-size: 8pt;\" aria-label=\"\u63a7\u91ca\u7247\u5242\u7684\u8fd1\u7ea2\u5916\u5149\u8c31 (1\u4e2a\u9879\u76ee)\">\u63a7\u91ca\u7247\u5242\u7684\u8fd1\u7ea2\u5916\u5149\u8c31<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e7%89%87%e5%89%82%e6%bf%80%e5%85%89%e9%92%bb%e5%ad%94%e6%9c%ba\/\" class=\"tag-cloud-link tag-link-4 tag-link-position-5\" style=\"font-size: 8pt;\" aria-label=\"\u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a (1\u4e2a\u9879\u76ee)\">\u7247\u5242\u6fc0\u5149\u94bb\u5b54\u673a<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e7%ae%80%e5%8c%96%e6%b8%97%e9%80%8f%e8%8d%af%e7%89%a9%e7%9a%84%e8%be%93%e9%80%81\/\" class=\"tag-cloud-link tag-link-5 tag-link-position-6\" style=\"font-size: 8pt;\" aria-label=\"\u7b80\u5316\u6e17\u900f\u836f\u7269\u7684\u8f93\u9001 (1\u4e2a\u9879\u76ee)\">\u7b80\u5316\u6e17\u900f\u836f\u7269\u7684\u8f93\u9001<\/a>\n<a href=\"https:\/\/www.bihec.com\/brimrose\/tag\/%e8%bf%91%e7%ba%a2%e5%a4%96%e5%85%89%e8%b0%b1%e4%bb%aa\/\" class=\"tag-cloud-link tag-link-6 tag-link-position-7\" style=\"font-size: 19.145631067961pt;\" aria-label=\"\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea (87\u4e2a\u9879\u76ee)\">\u8fd1\u7ea2\u5916\u5149\u8c31\u4eea<\/a><\/div>","protected":false},"excerpt":{"rendered":"<p>Near-Infrared Spectroscopy for Controlled Release Tablets Osmotic drug delivery has been s <\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_vp_format_video_url":"","_vp_image_focal_point":[]},"categories":[19],"tags":[651,34,654,653,650,652,26],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v17.5 - 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